What's your opinion about the single best (most effective or highest success rate) way to make money online?

I suppose you ultimately make more from selling something than from screening ads, I have not made more than $100/month from ads, and that's on sites with 30k visitors per month.

If you've got a lot of unique and well-written content, and submit your site to directories and search engines, should it result in success? Or are there other factors involved? What's your experience and best strategy? -- or best strategy that you'd be willing to share ; )

affiliate programs could be very profitable

Hey...
I am quite agree with you that affiliate is one of the best way to make money online... Millions of peoples have joined it and they are making money through it.... it is quite easy and simple